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یکی از مهمترین اقداماتی که می‌توان جهت کنترل فشار خون (و در نتیجه پیشگیری از بیماری‌های قلبی) انجام داد، حفظ وزن در یک محدوده سالم می‌باشد. در افراد دچار اضافه وزن نسبت به افراد دارای وزن سالم و طبیعی، میزان خطر ابتلا به فشار خون ۲ برابر می‌شود. اگر تنها ۵/۴ کیلوگرم اضافه وزن نسبت به مقدار مطلوب داشته باشید، کاهش این مقدار اضافه وزن به طور قابل توجهی می‌تواند فشارخون را کاهش دهد.

وزن با عوامل دیگری چون سطح کلسترول و خطر ابتلا به دیابت در ارتباط بوده و از این رو از راه‌های مختلفی سلامت قلبی عروقی را تحت تأثیر قرار می‌دهد.
درک ارتباط میان وزن و فشار خون ساده است. با افزایش وزن، بافت چربی افزایش می‌یابد.  بافت چربی نیز مانند هر بافت دیگری در بدن‌، جهت زنده ماندن نیاز به اکسیژن و موادغذایی دارد. با افزایش بافت چربی‌، میزان خون موجود در دستگاه گردش خون بدن نیز باید افزایش یابد. در نتیجه کلیه‌ها میزان آب و سدیم  بیشتری را در بدن حفظ می‌نمایند که منجر به افزایش فشار خون می‌شود. هنگامیکه وزن خود را کاهش می‌دهید، این اثرات منفی معکوس می‌گردند و فشار خون به محدوده سالم تر بر‌می‌گردد.

منبع: بیمارستان شهید رجایی

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